If you want your manuscript (it may make you sound smarter to call it your "treatise" or "monograph") to actually get published, try something like Medical Hypotheses. Journals with an impact factor of less than 1 might actually be desperate enough to publish something cranky, especially if you can jargonize it enough to make yourself sound smart, or create enough fake data to trick the editors. If it has to do with global warming consider a Wall Street Journal Op-Ed. The Creation Research Quarterly is perfect for anything disproving some facet of evolution, geology, astronomy, or physics. You don't have to be a creationist for them to like your crank theory, anything that pokes holes in dastardly consensus science is a victory.
Then try journals that don't require real experiments, rigorous trial design, peer review or anything that actually indicates actual science has been done. Other cranks in your "field" may have started just such a journal - like the Journal of 9/11 studies. There are about as many places that will publish crank work as there are crank ideas, don't stop trying! If you get your ideas published in such a journal claim victory! You have mainstream acceptance and a publication record now.
Physics Essays anyone?
Or how about how to deal with dissenters:
Accusation: "You haven't published in a real peer-reviewed journal"
Response: Either say "Peer review is just an old-boys network for peon scientists to pat each other on the back", or accuse journal editors of persecuting you. Compare yourself to Galileo.
Accusation: "You don't have solid proof"
Response: Either restate what you said already, restate it slightly differently, call your accuser a name, or suggest they are part of the conspiracy to hide the truth. Compare yourself to Galileo.
This just reminds me of the autodynamics page where they have a picture of Carezani with Einstein, Newton, and Galileo fading off behind him.
I'm sure you'll all be able to spot some of your favourite cranky behaviour in the post, it certainly saved me the time an effort of going an writing a post along those lines.